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This clarifies why one lorazepam dose, despite its shorter serum 50 percent-everyday living, has more prolonged peak results than an equal diazepam dose.[ninety nine] Lorazepam is promptly conjugated at its 3-hydroxy group into lorazepam glucuronide that is then excreted inside the urine. Lorazepam glucuronide has no demonstrable CNS activity in an